Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Decrease in serum procalcitonin levels over time during treatment of acute bacterial meningitis. | Available online http content 9 4 R344 Research Decrease in serum procalcitonin levels over time during treatment of acute bacterial meningitis Alain Viallon1 Pantéa Guyomarc h1 Stéphane Guyomarc h1 Bernard Tardy1 Florianne Robert1 Olivier Marjollet1 Anne Caricajo2 Claude Lambert3 Fabrice Zéni1 and Jean-Claude Bertrand1 Emergency and Intensive Care Units Bellevue Hospital Saint-Etienne France 2Microbiology Laboratory Bellevue Hospital Saint-Etienne France 3Immunology Laboratory Bellevue Hospital Saint-Etienne France Corresponding author Alain Viallon Received 23 Feb 2005 Revisions requested 9 Mar 2005 Revisions received 25 Apr 2005 Accepted 27 Apr 2005 Published 20 May 2005 Critical Care 2005 9 R344-R350 DOI 86 cc3722 This article is online at http content 9 4 R344 2005 Viallon et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The aim of this study was to describe the change in serum proealeitonin levels during treatment for community-acquired acute bacterial meningitis. Methods Out of 50 consecutive patients presenting with bacterial meningitis and infection at no other site and who had received no prior antibiotic treatment 48 had a serum procalcitonin level above ng ml on admission and were enrolled in the study. Results The mean age of the patients was 55 years and mean Glasgow Coma Scale score on admission was 13. The time from symptom onset to admission was less than 24 hours in 40 of the patients 24-48 hours in 20 and more than 48 hours in 40 . The median interquartile interval between admission and initial antibiotic treatment was 160 min 60-280 min . Bacterial infection was documented in 45 patients. Causative .
