Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Short-term effects of positive end-expiratory pressure on breathing pattern: an interventional study in adult intensive care patients. | Available online http content 9 4 R407 Research Short-term effects of positive end-expiratory pressure on breathing pattern an interventional study in adult intensive care patients Christoph Haberthur1 and Josef Guttmann2 Assistant Professor and head of Surgical Intensive Care Medicine Department of Anaesthesia Kantonsspital Luzern Switzerland 2Professor in Biomedical Engineering Section of Experimental Anaesthesiology Department of Anaesthesia and Critical Care Medicine University of Freiburg Germany Corresponding author Christoph Haberthur Received 13 Jan 2005 Revisions requested 16 Feb 2005 Revisions received 18 Apr 2005 Accepted 11 May 2005 Published 9 Jun 2005 Critical Care 2005 9 R407-R415 DOI cc3735 This article is online at http content 9 4 R407 2005 Haberthur and Guttmann licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Positive end-expiratory pressure PEEP is used in mechanically ventilated patients to increase pulmonary volume and improve gas exchange. However in clinical practice and with respect to adult ventilator-dependent patients little is known about the short-term effects of PEEP on breathing patterns. Methods In 30 tracheally intubated spontaneously breathing patients we sequentially applied PEEP to the trachea at 0 5 and 10 cmH2O and then again at 5 cmH2O for 30 s each using the automatic tube compensation mode. Results Increases in PEEP were strongly associated with drops in minute ventilation P and respiratory rate P . For respiratory rate a 1 cmH2O change in PEEP in either direction resulted in a change in rate of breaths min. The effects were exclusively due to changes in expiratory time. .
