Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical review: The meaning of acid–base abnormalities in the intensive care unit – epidemiology. | Critical Care October 2005 Vol 9 No 5 Gunnerson Review Clinical review The meaning of acid-base abnormalities in the intensive care unit - epidemiology Kyle J Gunnerson Assistant Professor The Virginia Commonwealth University Reanimation Engineering and Shock Center VCURES Laboratory Departments of Anesthesiology Critical Care and Emergency Medicine Virginia Commonwealth University Medical Center Richmond Virginia USA Corresponding author Kyle Gunnerson kgunnerson@ Published online 10 August 2005 This article is online at http content 9 5 508 2005 BioMed Central Ltd Critical Care 2005 9 508-516 DOI cc3796 Abstract Acid-base abnormalities are common in critically ill patients. Our ability to describe acid-base disorders must be precise. Small differences in corrections for anion gap different types of analytical processes and the basic approach used to diagnose acid-base aberrations can lead to markedly different interpretations and treatment strategies for the same disorder. By applying a quantitive acid-base approach clinicians are able to account for small changes in ion distribution that may have gone unrecognized with traditional techniques of acid-base analysis. Outcome prediction based on the quantitative approach remains controversial. This is in part due to use of various technologies to measure acid-base variables administration of fluid or medication that can alter acid-base results and lack of standardized nomenclature. Without controlling for these factors it is difficult to appreciate the full effect that acid-base disorders have on patient outcomes ultimately making results of outcome studies hard to compare. Introduction Critically ill and injured patients commonly have disorders of acid-base equilibrium. Acidosis may occur as a result of increases in arterial partial carbon dioxide tension Pco2 respiratory acidosis or from a variety organic or inorganic fixed acids metabolic acidosis . There appears to be a difference in .
