Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis. | Available online http content 9 5 R591 Research Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis Lui G Forni1 William McKinnon2 Gwyn A Lord3 David F Treacher4 Jean-Marie R Peron5 and Philip J Hilton6 Consultant Physician Intensivist Department of Critical Care Worthing Hospital Worthing West Sussex UK 2Research Fellow Renal Laboratory St Thomas Hospital London UK 3MRC Scientist MRC Toxicology Unit Birkbeck College London UK 4Consultant Physician Intensivist Renal Laboratory St Thomas Hospital London UK 5Research Fellow Department of Chemistry Kingston University Surrey UK 6Consultant Physician Research Director Renal Laboratory St Thomas Hospital London UK Corresponding author Lui G Forni Received 29 Jun 2005 Revisions requested 22 Jul 2005 Revisions received 1 Aug 2005 Accepted 12 Aug 2005 Published 13 Sep 2005 Critical Care 2005 9 R591-R595 DOI cc3806 This article is online at http content 9 5 R591 2005 Forni et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Acute metabolic acidosis of non-renal origin is usually a result of either lactic or ketoacidosis both of which are associated with a high anion gap. There is increasing recognition however of a group of acidotic patients who have a large anion gap that is not explained by either keto- or lactic acidosis nor in most cases is inappropriate fluid resuscitation or ingestion of exogenous agents the cause. Methods Plasma ultrafiltrate from patients with diabetic ketoacidosis lactic acidosis acidosis of unknown cause normal anion gap metabolic acidosis or acidosis as a result of base loss were examined enzymatically for the presence of .
