Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài:Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study. | Available online http content 9 6 R601 Research Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients a prospective validation study E Christiaan Boerma1 2 Keshen R Mathura1 Peter HJ van der Voort2 Peter E Spronk1 3 and Can Ince1 Department of Physiology Academic Medical Centre University of Amsterdam The Netherlands 2Department of Intensive Care Medical Centre Leeuwarden The Netherlands 3Department of Intensive Care Gelre Ziekenhuizen Apeldoorn The Netherlands Corresponding author E Christiaan Boerma Received 10 Aug 2005 Accepted 25 Aug 2005 Published 22 Sep 2005 Critical Care 2005 9 R601-R606 DOI cc3809 This article is online at http content 9 6 R601 2005 Boerma et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The introduction of orthogonal polarization spectral OPS imaging in clinical research has elucidated new perspectives on the role of microcirculatory flow abnormalities in the pathogenesis of sepsis. Essential to the process of understanding and reproducing these abnormalities is the method of quantification of flow scores. Methods In a consensus meeting with collaboraters from six research centres in different fields of experience with microcirculatory OPS imaging premeditated qualifications for a simple translucent and reproducible way of flow scoring were defined. Consecutively a single-centre prospective observational validation study was performed in a group of 12 patients with an abdominal sepsis and a new stoma. Flow images of the microcirculation in vascular beds of the sublingual and stoma region were obtained processed and analysed in a standardised way. We validated intra-observer
