Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445]. | Available online http content 9 6 R687 Research Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised controlled trial ISRCTN38797445 Rupert Pearse Deborah Dawson Jayne Fawcett Andrew Rhodes R Michael Grounds and E David Bennett Open Access Adult Intensive Care Unit 1st floor St James Wing St George s Hospital Blackshaw Road London SW17 0QT UK Corresponding author Rupert Pearse Received 8 Sep 2005 Accepted 30 Sep 2005 Published 8 Nov 2005 Critical Care 2005 9 R687-R693 DOI 86 cc3887 This article is online at http content 9 6 R687 2005 Pearse et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Goal-directed therapy GDT has been shown to improve outcome when commenced before surgery. This requires pre-operative admission to the intensive care unit ICU . In cardiac surgery GDT has proved effective when commenced after surgery. The aim of this study was to evaluate the effect of post-operative GDT on the incidence of complications and duration of hospital stay in patients undergoing general surgery. Methods This was a randomised controlled trial with concealed allocation. High-risk general surgical patients were allocated to post-operative GDT to attain an oxygen delivery index of 600 ml min-1 m-2 or to conventional management. Cardiac output was measured by lithium indicator dilution and pulse power analysis. Patients were followed up for 60 days. Results Sixty-two patients were randomised to GDT and 60 patients to control treatment. The GDT group received more intravenous colloid 1 907 SD 878 ml versus 1 204 SD 898 ml p and dopexamine 55 patients 89 versus 1 patient 2 p
