Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Can we predict septic shock in patients with hospital-acquired pneumonia? | Critical Care December 2005 Vol 9 No 6 de Lange and Bonten Commentary Can we predict septic shock in patients with hospital-acquired pneumonia Dylan W de Lange1 and Marc JM Bonten2 1 Department of Intensive Care Medicine and Department of Internal Medicine Infectious Diseases Division of General Medicine Infectious Diseases Geriatrics University Medical Center Utrecht Utrecht The Netherlands 2Department of Internal Medicine Infectious Diseases Division of General Medicine Infectious Diseases Geriatrics Department of Medical Microbiology Division of Hospital Hygiene Infection Prevention Julius Center for Health Care Epidemiology Primary Care University Medical Center Utrecht Utrecht The Netherlands Corresponding author Marc JM Bonten mbonten@ Published online 11 November 2005 Critical Care 2005 9 640-641 DOI cc3919 This article is online at http content 9 6 640 2005 BioMed Central Ltd See related research by von Dossow et al. in this issue http content 9 6 R662 Abstract Hospital-acquired pneumonia is a serious and potentially lifethreatening complication with reported pneumonia-attributable mortality rates as high as 50 . Rapid diagnosis and immediate institution of adequate empirical antimicrobial treatment are of paramount importance in patient management. Nevertheless some patients deteriorate and develop respiratory insufficiency septic shock and a multiorgan dysfunction syndrome. Early recognition of these patients might help in reducing morbidity and mortality. Elevated systemic levels of proinflammatory cytokines IL-1P IL-6 IL-8 and IL-10 at the time of diagnosis of hospital-acquired pneumonia appear to be indicative of subsequent progression to septic shock. Should this now become a part of patient management In the present issue of Critical Care van Dossow and coworkers 1 report their findings in predicting progression from hospital-acquired pneumonia HAP to septic shock based on systemic levels of .
