Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A Continuous infusion of ceftazidime in critically ill patients undergoing continuous venovenous haemodiafiltration: pharmacokinetic evaluation and dose recommendation. | Available online http content 10 1 R26 Research Continuous infusion of ceftazidime in critically ill patients undergoing continuous venovenous haemodiafiltration pharmacokinetic evaluation and dose recommendation Christophe Mariat1 Christophe Venet2 Franpois Jehl3 Sandrine Mwewa4 Vesna Lazarevic4 Eric Diconne2 Nathalie Fonsale5 Anne Carricajo5 Stéphane Guyomarc h2 Régine Vermesch2 Gérald Aubert5 Roselyne Bidault4 Jean-Claude Bertrand2 and Fabrice Zeni2 Service de Néphrologie Hôpital Nord CHU de Saint-Etienne Saint-Etienne France 2Service d Urgences et de Réanimation Hôpital Bellevue CHU de Saint-Etienne St Etienne France 3Laboratoire de Bactériologie Faculté de Médecine Strasbourg France 4Unité de Pharmacologie Clinique Laboratoire Glaxo Wellcome Marly Le Roi France 5Service de Bactériologie Hôpital Bellevue CHU de Saint-Etienne St Etienne France Corresponding author Christophe Mariat Received 6 Oct 2005 Revisions requested 15 Nov 2005 Revisions received 12 Dec 2005 Accepted 16 Jan 2006 Published 13 Feb 2006 Critical Care 2006 10 R26 doi cc3993 This article is online at http content 10 1 R26 2006 Mariat et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction In seriously infected patients with acute renal failure and who require continuous renal replacement therapy data on continuous infusion of ceftazidime are lacking. Here we analyzed the pharmacokinetics of ceftazidime administered by continuous infusion in critically ill patients during continuous venovenous haemodiafiltration CVVHDF in order to identify the optimal dosage in this setting. Method Seven critically ill patients were prospectively enrolled in the study. .
