Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A Effects of coagulation factor XIII on intestinal functional capillary density, leukocyte adherence and mesenteric plasma extravasation in experimental endotoxemia. | Available online http content 10 1 R29 Research Effects of coagulation factor XIII on intestinal functional capillary density leukocyte adherence and mesenteric plasma extravasation in experimental endotoxemia Jurgen Birnbaum1 Ortrud Vargas Hein1 Carsten Luhrs1 Oskar Ruckbeil1 Claudia Spies1 Sabine Ziemer2 Matthias Grundling3 Taras Usichenko3 Konrad Meissner3 Dragan Pavlovic3 Wolfgang J Kox1 and Christian Lehmann3 1Klinik fur Anaesthesiologie und operative Intensivmedizin Charité - Universitatsmedizin Berlin Campus Charité Mitte 10117 Berlin Schumannstr. Germany 2Insitut fur Laboratoriumsmedizin und Pathobiochemie Charité - Universitatsmedizin Berlin Campus Charité Mitte 10117 Berlin Schumannstr. Germany 3Klinik fur Anasthesiologie und Intensivmedizin Ernst-Moritz-Arndt-Universitat Greifswald 1 7489 Greifswald . Germany Corresponding author Jurgen Birnbaum Received 27 Sep 2005 Revisions requested 8 Dec 2005 Revisions received 3 Jan 2006 Accepted 18 Jan 2006 Published 13 Feb 2006 Critical Care 2006 10 R29 doi cc3994 This article is online at http content 10 1 R29 2006 Birnbaum et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The objective of this study was to determine the effects of the administration of the coagulation factor XIII F XIII on intestinal functional capillary density leukocyte adherence and mesenteric plasma extravasation during experimental endotoxemia. Methods In a prospective randomized controlled animal study 42 male Wistar rats were divided into three groups. Group 1 served as the control group. Groups 2 lipopolysaccharide LPS group and 3 F XIII group received endotoxin infusions mg kg h