Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Retrovirology cung cấp cho các bạn kiến thức về ngành y đề tài: " Ethnic differences in the adaptation rate of HIV gp120 from a vaccine trial. | Retrovirology BioMed Central Open Access Short report Ethnic differences in the adaptation rate of HIV gp120 from a vaccine trial Marcos Perez-Losada 1 David Posada2 Miguel Arenas2 David V Jobes3 Faruk Sinangil4 Phillip W Berman5 and Keith A Crandall6 Address 1CIBIO Centro de Investigaẹão em Biodiversidade e Recursos Genéticos Universidade do Porto Campus Agrário de Vairão 4485-661 Vairão Portugal 2Departamento de Bioquímica Genética e Inmunología. Universidad de Vigo 36310 Vigo Spain 3Presidio Pharmaceuticals Inc. San Francisco CA 94158 USA 4Global Solutions for Infectious Diseases South San Francisco CA 94080 USA department of Biomolecular Engineering University of California Santa Cruz CA 95064 USA and department of Biology Brigham Young University Provo UT 84602 USA Email Marcos Perez-Losada - mlosada@ David Posada - dposada@ Miguel Arenas - miguelab@ David V Jobes - djobes@ Faruk Sinangil - fsinagil@ Phillip W Berman - pwb@ Keith A Crandall - kcrandall@ Corresponding author Published 15 July 2009 Received 3 May 2009 Retrovirology 2009 6 67 doi 1742-4690-6-67 Accepted I5 July 2009 This article is available from http content 6 1 67 2009 Pérez-Losada et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Differences in HIV-1 gp120 sequence variation were examined in North American volunteers who became infected during a phase III vaccine trial using the rgp120 vaccine. Molecular adaptation of the virus in vaccine and placebo recipients from different ethnic subgroups was compared by estimating the dN dS ratios in viruses sampled from each individual using three different methods. ANOVA analyses detected .
