Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Retrovirology cung cấp cho các bạn kiến thức về ngành y đề tài: RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy. | Retrovirology BioMed Central Research RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy Wei Shao 1 Mary Kearney2 Frank Maldarelli2 John W Mellors3 Robert M Stephens1 Jeffrey D Lifson4 Vineet N KewalRamani2 Zandrea Ambrose3 John M Coffin5 and Sarah E Palmer2 6 Address Advanced Biomedical Computing Center SAIC Frederick Inc National Cancer Institute at Frederick Frederick MD USA 2HIV Drug Resistance Program NCI Frederick MD USA 3Division of Infectious Diseases University of Pittsburgh School of Medicine Pittsburgh PA USA 4AIDS and Cancer Virus Program SAIC Frederick Inc National Cancer Institute at Frederick Frederick MD USA 5Tufts University Boston MA USA and department of Virology Swedish Institute for Infectious Disease Control and Karolinska Institutet Stockholm Sweden Email Wei Shao - shaow@ Mary Kearney - kearneym@ Frank Maldarelli - fmalli@ John W Mellors - Mellors@ Robert M Stephens - stephensr@ Jeffrey D Lifson - Vineet N KewalRamani - vineet@ Zandrea Ambrose - zaa4@ John M Coffin - coffinj@ Sarah E Palmer - Corresponding author Open Access Published 4 November 2009 Received 14 September 2009 Accepted 4 November 2009 Retrovirology 2009 6 101 doi l742-4690-6-101 This article is available from http content 6 1 101 2009 Shao et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background To study the dynamics of wild-type and drug-resistant HIV-1 RT variants we developed a methodology that follows the fates of individual genomes over time within the viral quasispecies. Single genome sequences were obtained from 3 pigtail .
