Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Failure of non-invasive ventilation in patients with acute lung injury: observational cohort study. | Available online http content 10 3 R79 Research Failure of non-invasive ventilation in patients with acute lung injury observational cohort study Sameer Rana1 Hussam Jenad1 Peter C Gay1 Curtis F Buck2 Rolf D Hubmayr1 and Ognjen Gajic1 Department of Internal Medicine Division of Pulmonary and Critical Care Medicine Mayo Clinic Rochester Minnesota USA department of Anesthesiology Division of Intensive Care and Respiratory Care Mayo Clinic Rochester Minnesota USA Corresponding author Ognjen Gajic Received 3 Jan 2006 Revisions requested 31 Jan 2006 Revisions received 15 Feb 2006 Accepted 1 9 Apr 2006 Published 12 May 2006 Critical Care 2006 10 R79 doi cc4923 This article is online at http content 10 3 R79 2006 Rana et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The role of non-invasive positive pressure ventilation NIPPV in the treatment of acute lung injury ALI is controversial. We sought to assess the outcome of ALI that was initially treated with NIPPV and to identify specific risk factors for NIPpV failure. Methods In this observational cohort study at the two intensive care units of a tertiary center we identified consecutive patients with ALI who were initially treated with NIPPV. Data on demographics APACHE III scores degree of hypoxemia ALI risk factors and NIPPV respiratory parameters were recorded. Univariate and multivariate regression analyses were performed to identify risk factors for NIPPV failure. Results Of 79 consecutive patients who met the inclusion criteria 23 were excluded because of a do not resuscitate order and two did not give research authorization. Of the remaining 54 patients 38 failed NIPPV among .
