Báo cáo y học: "Recently published papers: Pandemic flu, the latest ARDS trials, raising legs and other stories"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Recently published papers: Pandemic flu, the latest ARDS trials, raising legs and other stories. | Available online http content 10 3 143 Commentary Recently published papers Pandemic flu the latest ARDS trials raising legs and other stories Jonathan Ball General Intensive Care Unit St George s Hospital London SW17 0QT UK Corresponding author Jonathan Ball jball@ Published 25 May 2006 This article is online at http content 10 3 143 2006 BioMed Central Ltd Critical Care 2006 10 143 doi cc4943 Abstract In this commentary recent papers covering pandemic influenza acute respiratory distress syndrome and cardiovascular issues are discussed. Pandemic influenza preparedness and novel therapy The burning question about pandemic flu is when not if it will strike. Given this general consensus and the proven benefits of planning for such emergencies it was timely to read the results of an independent evaluation of preparedness in Europe 1 . As one might expect the news is a classical mixture of good and bad with perhaps the most worrying deficit being an almost systematic absence of cooperation and communication between neighbouring states. This is exemplified by the fact that only three countries have undertaken simulation exercises the results of which have yet to reach the public domain. We can only hope that the clear messages emerging from this study are acted upon by governments worldwide. At the opposite end of the spectrum an illuminating treatment hypothesis for some of the severest human cases of H5N1 avian influenza A has been proposed by a collaborative team from Sweden and Hong Kong 2 . Patients contracting this infection may develop haemophagocytic lymphohistiocytosis which in turn causes multi-organ failure and death. These authors put forward a convincing argument to consider treating such patients with a combination of dexamethasone and the cytotoxic etoposide. They suggest given the epidemiology of this disease that the WHO should consider undertaking a clinical trial of this therapeutic approach. For a more .

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