Báo cáo y học: " Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding. | Available online http content 10 4 R104 Research Pharmacokinetics of recombinant activated factor VII in trauma patients with severe bleeding Thomas Klitgaard1 Rene Tabanera y Palacios2 Kenneth D Boffard3 Philip TC Iau4 Brian Warren5 Sandro Rizoli6 Rolf Rossaint7 Yoram Kluger8 Bruno Riou9 and the NovoSeven Trauma Study Group Department of Biomodelling Novo Nordisk A S Maaloev Denmark department of Biostatistics Novo Nordisk A S Bagsvaerd Denmark department of Surgery Johannesburg Hospital Houghton Johannesburg South Africa department of Surgery National University Hospital Singapore department of Surgery Tygerberg Hospital University of Stellenbosch Tygerberg South Africa departments of Surgery and Critical Care Medicine Sunnybrook and Women s College Health Sciences Centre University of Toronto Toronto Ontario Canada department of Anesthesiology University Clinics Aachen Germany department of Surgery Haifa Medical Center Haifa Israel department of Emergency Medicine and Surgery and Department of Anesthesiology and Critical Care Hôpital Pitié-Salpêtrière Assistance Publique-Hôpitaux de Paris Université Pierre et Marie Curie-Paris 6 Paris France Corresponding author Bruno Riou Received 11 May 2006 Revisions requested 19 Jun 2006 Revisions received 26 Jun 2006 Accepted 30 Jun 2006 Published 1 9 Jul 2006 Critical Care 2006 10 R104 doi cc4977 This article is online at http content 10 4 R1 04 2006 Klitgaard et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Recombinant activated factor VII rFVIla has been used as adjunctive therapy in trauma patients with severe bleeding. However its pharmacokinetics profile remains unknown. Methods In .

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