Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Efficacy and safety of a low-flow veno-venous carbon dioxide removal device: results of an experimental study in adult sheep. | Available online http content 10 5 R151 Open Access Research Efficacy and safety of a low-flow veno-venous carbon dioxide removal device results of an experimental study in adult sheep Sergio Livigni1 Mariella Maio1 Enrica Ferretti1 Annalisa Longobardo1 Raffaele Potenza1 Luca Rivalta1 Paola Selvaggi1 Marco Vergano1 and Guido Bertolini2 Department of Anaesthesia and Intensive Care Ospedale Torino Nord Emergenza San Giovanni Bosco Piazza del Donatore di Sangue 3 10154 Turin Italy 2GiViTI Coordinating Center Laboratory of Clinical Epidemiology Mario Negri Institute for Pharmacological Research Villa Camozzi Via Camozzi 2 24020 Ranica Bergamo Italy Corresponding author Sergio Livigni s_livigni@ Received 22 Aug 2006 Revisions requested 27 Sep 2006 Revisions received 10 Oct 2006 Accepted 28 Oct 2006 Published 28 Oct 2006 Critical Care 2006 10 R151 doi cc5082 This article is online at http content 10 5 R151 2006 Livigni et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Extracorporeal lung assist an extreme resource in patients with acute respiratory failure ARF is expanding its indications since knowledge about ventilator-induced lung injury has increased and protective ventilation has become the standard in ARF. Methods A prospective study on seven adult sheep was conducted to quantify carbon dioxide CO2 removal and evaluate the safety of an extracorporeal membrane gas exchanger placed in a veno-venous pump-driven bypass. Animals were anaesthetised intubated ventilated in order to reach hypercapnia and then connected to the CO2 removal device. Five animals were treated for three hours one for nine hours and one for 12 hours. At the end of the experiment general
