Báo cáo khoa học: " Outcome of postoperative critically ill patients with heparin-induced thrombocytopenia: an observational retrospective case-control study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Outcome of postoperative critically ill patients with heparin-induced thrombocytopenia: an observational retrospective case-control study. | Available online http content 10 6 R161 Research Outcome of postoperative critically ill patients with heparin-induced thrombocytopenia an observational retrospective case-control study Elise M Gettings1 Kathryn A Brush2 Elizabeth M Van Cott3 and William E Hurford1 1 Department of Anesthesia and Critical Care Massachusetts General Hospital 55 Fruit Street Boston MA 02114 USA 2Department of Nursing Massachusetts General Hospital 55 Fruit Street Boston MA 02114 USA 3Department of Clinical Pathology Massachusetts General Hospital 55 Fruit Street Boston MA 0211 4 USA Corresponding author William E Hurford Received 31 Aug 2006 Revisions requested 10 Oct 2006 Revisions received 7 Nov 2006 Accepted 16 Nov 2006 Published 16 Nov 2006 Critical Care 2006 10 R161 doi cc5100 This article is online at http content 10 6 R161 2006 Gettings et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Heparin-induced thrombocytopenia HIT is described as a decrease in platelet count associated with heparin administration and is an immune-mediated adverse drug reaction that can cause both arterial and venous thromboses. It can be a life-threatening complication of heparin exposure. Little data concerning incidence predisposing factors or outcome in critically ill surgical patients are available. Methods All critically ill postoperative patients admitted between January 1 2000 and December 31 2001 to a surgical intensive care unit SICU who tested positive by an enzyme-linked immunosorbent assay for the HIT antibody HPIA Diagnostica Stago Inc. Parsippany NJ USA were identified. Patient risk factors and outcomes were abstracted retrospectively from the medical .

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