Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Mechanical ventilation and lung infection in the genesis of air-space enlargement. | Available online http content 11 1 R14 Open Access Research Mechanical ventilation and lung infection in the genesis of air-space enlargement Alfonso Sartorius1 Qin Lu1 Silvia Vieira2 Marc Tonnellier3 Gilles Lenaour4 Ivan Goldstein1 and Jean-Jacques Rouby1 Surgical Intensive Care Unit Pierre Viars Department of Anesthesiology Assistance Publique-Hôpitaux de Paris La Pitié-Salpêtrière Hospital 4783 boulevard de l Hôpital 75013 Paris France 2Department of Internal Medicine Faculty of Medicine Federal University from Rio Grande do Sul Intensive Care Unit Hospital de Clinicas de Porto Alegre Rua Ramiro Barcelos 2350 - 90035-903 Porto Alegre Rio Grande do Sul Brazil 3Medical Intensive Care Unit Assistance Publique-Hôpitaux de Paris La Pitié-Salpêtrière Hospital 47-83 boulevard de l Hôpital 75013 Paris France 4Department of Pathology Assistance Publique-Hôpitaux de Paris La Pitié-Salpêtrière Hospital 47-83 boulevard de l Hôpital 75013 Paris France Corresponding author Jean-Jacques Rouby Received 6 Jun 2006 Revisions requested 1 Aug 2006 Revisions received 22 Nov 2006 Accepted 2 Feb 2007 Published 2 Feb 2007 Critical Care 2007 11 R14 doi cc5680 This article is online at http content 11 1 R14 2007 Sartorius et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Air-space enlargement may result from mechanical ventilation and or lung infection. The aim of this study was to assess how mechanical ventilation and lung infection influence the genesis of bronchiolar and alveolar distention. Methods Four groups of piglets were studied non-ventilated-non-inoculated controls n 5 non-ventilated-inoculated n 6 ventilated-non-inoculated n 6 and ventilated-inoculated