Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial. | Available online http content 11 1 R24 Research Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients a randomized controlled trial Ivan Chytra Richard Pradl Roman Bosman Petr Pelnár Eduard Kasal and Alexandra Zidkova Department of Anesthesia and Intensive Care Medicine University Hospital Alej svobody 80 Plzen 30460 Czech Republic Corresponding author Ivan Chytra chytra@ Received 23 Oct 2006 Revisions requested 30 Nov 2006 Revisions received 8 Jan 2007 Accepted 22 Feb 2007 Published 22 Feb 2007 Critical Care 2007 11 R24 doi cc5703 This article is online at http content 11 1 R24 2007 Chytra et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Esophageal Doppler was confirmed as a useful non-invasive tool for management of fluid replacement in elective surgery. The aim of this study was to assess the effect of early optimization of intravascular volume using esophageal Doppler on blood lactate levels and organ dysfunction development in comparison with standard hemodynamic management in multiple-trauma patients. Methods This was a randomized controlled trial. Multipletrauma patients with blood loss of more than 2 000 ml admitted to the intensive care unit ICU were randomly assigned to the protocol group with esophageal Doppler monitoring and to the control group. Fluid resuscitation in the Doppler group was guided for the first 12 hours of ICU stay according to the protocol based on data obtained by esophageal Doppler whereas control patients were managed conventionally. Blood lactate levels and organ dysfunction during ICU stay were evaluated. Results Eighty patients were randomly assigned to Doppler
