Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Prognostic utility of RIFLE for acute renal failure in patients with sepsis. | Available online http content 11 2 408 Letter Prognostic utility of RIFLE for acute renal failure in patients with sepsis José António Lopes1 Sofia Jorge1 Cristina Resina1 Carla Santos2 Álvaro Pereira2 José Neves2 Francisco Antunes2 and Mateus Martins Prata1 1 Department of Nephrology and Renal Transplantation Hospital de Santa Maria Av. Prof. Egas Moniz 1649-035 Lisboa Portugal 2Department of Infectious Diseases Hospital de Santa Maria Av. Prof. Egas Moniz 1649-035 Lisboa Portugal Corresponding author José António Lopes jalopes93@ Published 5 April 2007 Critical Care 2007 11 408 doi cc5722 This article is online at http content 11 2 408 2007 BioMed Central Ltd Acute renal failure ARF is common among patients with sepsis and increases mortality 1 . However the prognostic utility of the newly released classification for ARF entitled RIFLE Risk Injury Failure Loss and End-stage kidney disease 2 in predicting mortality in such patients has not yet been assessed. We sought to evaluate retrospectively the usefulness of RIFLE in predicting mortality in patients with sepsis admitted to the infectious disease intensive care unit ICU of our hospital between January 2005 and December 2006. Data were collected from the unit database. Sepsis was classified in accordance with American College of Chest Physicians and the Society of Critical Care Medicine consensus 3 . Patients with chronic kidney disease on dialysis were excluded from the analysis. The Simplified Acute Physiology Score SAPS version II was calculated based on the worst variables recorded during the first 24 hours of ICU admission. Mortality was assessed at day 60 2 . Forward stepwise multivariate regression analysis was employed to evaluate independent predictors of mortality. The goodness-of-fit was tested by means of the Hosmer-Lemeshaw statistic. Area under the receiver operating characteristic curve AUROC was employed to evaluate the prognostic accuracy of RIFLE and