Available online Research Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Diagnostic yield of quantitative endotracheal aspirates in patients with severe nursing home-acquired pneumonia. | Available online http content 11 3 R57 Research Diagnostic yield of quantitative endotracheal aspirates in patients with severe nursing home-acquired pneumonia Ali A El Solh Morohunfolu E Akinnusi Lilibeth A Pineda and Corey R Mankowski Open Access Western New York Respiratory Research Center Division of Pulmonary Critical Care and Sleep Medicine Department of Medicine State University of New York at Buffalo School of Medicine and Biomedical Sciences Grider Street Buffalo New York 14215 USA Corresponding author Ali A El Solh solh@ Received 26 Mar 2007 Accepted 17 May 2007 Published 17 May 2007 Critical Care 2007 11 R57 doi cc5917 This article is online at http content 11 3 R57 2007 El Solh et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Diagnostic strategies based on tracheal aspirates in patients with severe nursing home-acquired pneumonia have not previously been evaluated. The objectives of the study were to investigate in patients with severe nursing home-acquired pneumonia the diagnostic value of quantitative endotracheal aspirate QEA cultures using increasing interpretative cutoff points as compared with bronchoalveolar lavage BAL and protected specimen brush PSB quantitative cultures. Methods Seventy-five nursing home patients requiring mechanical ventilation for suspected pneumonia were studied. Endotracheal aspirate PSB and BAL samples were obtained consecutively. The diagnostic yield of QEA at thresholds raging from 103 to 107 colony-forming units cfu ml was assessed by calculating sensitivities specificities and accuracy rates. A receiver operator characteristic curve for the series of cutoff points was constructed. Results Forty-nine .
