Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. | Retrovirology BioMed Central Research Lysine methylation of HIV-I Tat regulates transcriptional activity of the viral LTR Rachel Van Duyne1 Rebecca Easley1 Weilin Wu1 Reem Berro1 Caitlin Pedati1 Zachary Klase1 Kylene Kehn-Hall1 Elizabeth K Flynn2 David E Symer3 and Fatah Kashanchi 1 4 Address rhe George Washington University Medical Center Department of Biochemistry and Molecular Biology Washington DC 20037 USA 2Basic Research Laboratory Center for Cancer Research National Cancer Institute Frederick MD 21702 USA 3Basic Research Laboratory and Laboratory of Biochemistry and Molecular Biology Center for Cancer Research National Cancer Institute Frederick MD 21702 USA and . Keck Institute for Proteomics Technology and Applications Washington DC 20037 USA Email Rachel Van Duyne - bcmrvv@ Rebecca Easley - bcmrle@ Weilin Wu - bcmwxw@ Reem Berro - ramroom@ Caitlin Pedati - bcmcsp@ Zachary Klase - bcmzak@ Kylene Kehn-Hall - bcmkwk@ Elizabeth K Flynn - flynn@ David E Symer - symerd@ Fatah Kashanchi - bcmfxk@ Corresponding author Open Access Published 22 May 2008 Received 3 January 2008 Retrovirology 2008 5 40 doi 1742-4690-5-40 Accepted 22 May 2008 This article is available from http content 5 1 40 2008 Van Duyne et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The rate of transcription of the HIV-1 viral genome is mediated by the interaction of the viral protein Tat with the LTR and other transcriptional machinery. These specific interactions can be affected by the state of post-translational .
