Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat. | Retrovirology BioMed Central Open Access Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat Caroline Egelé1 2 Pascale Barbier2 Pascal Didier1 Etienne Piémont1 Diane Allegro2 Olivier Chaloin3 Sylviane Muller3 Vincent Peyrot2 and Yves Mély 1 Address 1Université Louis Pasteur Strasbourg 1 Institut Gilbert Laustriat CNRS UMR 7175 Département Photophysique des Interactions Biomoléculaires Faculté de Pharmacie 74 Route du Rhin 67401 Illkirch Cedex France 2Aix-Marseille Université INSERM UMR 911 Centre de Recherche en Oncologie biologique et en Oncopharmacologie Faculté de Pharmacie 27 Boulevard Jean Moulin 13385 Marseille Cedex 5 France and 3CNRS UPR 9021 Institut de Biologie Moléculaire et Cellulaire 15 rue René Descartes Strasbourg France Email Caroline Egelé - Pascale Barbier-barbier@ Pascal Etienne Piémont - Diane Allegro - allegro@ Olivier Chaloin - Sylviane Muller - Vincent Peyrot - Yves Mély - mely@ Corresponding author Published 9 July 2008 Received 25 April 2008 Retrovirology 2008 5 62 doi 1742-4690-5-62 Accepted 9 July 2008 This article is available from http content 5 1 62 2008 Egelé et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background During HIV-1 infection the Tat protein plays a key role by transactivating the transcription of the HIV-1 proviral DNA. In addition Tat .
