Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication. | Retrovirology BioMed Central Open Access Contribution of the C-terminal region within the catalytic core domain of HIV-I integrase to yeast lethality chromatin binding and viral replication Zaikun Xu11 Yingfeng Zheng11 Zhujun Ao1 Martin Clement2 Andrew J Mouland3 Ganjam V Kalpana4 Pierre Belhumeur2 Éric A Cohen2 5 and XiaoJian Yao 1 Address laboratory of Molecular Human Retrovirology Department of Medical Microbiology University of Manitoba 508-730 William Avenue Winnipeg R3E 0W3 Canada 2Département de microbiologie et immunologie Université de Montreal Montreal H3C 3J7 Canada 3Lady Davis Institute for Medical Research and McGill University 3999 Cote-Ste-Catherine Montreal H3T 1E2 Canada 4Department of Molecular Genetics Albert Einstein College of Medicine 1300 Morris Park Ave U821 Bronx NY 10461 USA and laboratory of Human Retrovirology Institut de Recherches Cliniques de Montreal Montreal H2W 1R7 Canada Email Zaikun Xu - xuzaikun@ Yingfeng Zheng - umzhen28@ Zhujun Ao - ao@ Martin Clement - Andrew J Mouland - Ganjam V Kalpana - kalpana@ Pierre Belhumeur - Éric A Cohen - XiaoJian Yao - yao2@ Corresponding author fEqual contributors Published 14 November 2008 Received I August 2008 Accepted 14 November 2008 Retrovirology 2008 5 102 doi 1742-4690-5- 102 This article is available from http content 5 1 102 2008 Xu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background HIV-1 integrase IN is a key viral enzymatic molecule required for the integration of the viral cDNA into the genome. Additionally HIV-1 IN has .
