Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " HIV-1 sequence evolution in vivo after superinfection with three viral strains. | Retrovirology BioMed Central Research Open Access HIV-1 sequence evolution in vivo after superinfection with three viral strains Karolina Kozaczynska1 Marion Cornelissen1 Peter Reiss2 Fokla Zorgdrager1 and Antoinette C van der Kuyl 1 Address 1 Laboratory of Experimental Virology Department of Medical Microbiology Centre for Infection and Immunity Amsterdam CINIMA Academic Medical Centre of the University of Amsterdam Meibergdreef 15 1105 AZ Amsterdam The Netherlands and 2Department of Internal Medicine Division of Infectious Diseases Tropical Medicine and AIDS Academic Medical Centre of the University of Amsterdam Meibergdreef 15 1105 AZ Amsterdam The Netherlands Email Karolina Kozaczynska- Marion Cornelissen - Peter Reiss - Fokla Zorgdrager - Antoinette C van der Kuyl - Corresponding author Published 23 August 2007 Received 22 June 2007 Retrovirology 2007 4 59 doi l742-4690-4-59 Accepted 23 August 2007 This article is available from http content 4 1 59 2007 Kozaczynska et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract With millions of people infected worldwide the evolution of HIV-1 in vivo has been the subject of much research. Although recombinant viruses were detected early in the epidemic evidence that HIV-1 dual infections really occurred came much later. Dual infected patients consisting of coinfected second infection before seroconversion and superinfected second infection after seroconversion individuals opened up a new area of HIV-1 evolution studies. Here we describe the in-depth analysis of HIV-1 over time in a patient twice superinfected with HIV-1 .
