Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages. | Retrovirology BioMed Central Research Open Access HIV-I infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages Dinushka Dowling1 Somayeh Nasr-Esfahani1 Chun H Tan1 Kate O Brien1 Jane L Howard2 David A Jans3 Damian FJ Purcell2 C Martin Stoltzfus4 and Secondo Sonza 1 5 Address 1Macfarlane Burnet Institute for Medical Research and Public Health Melbourne Victoria Australia 2Department of Microbiology and Immunology University of Melbourne Melbourne Victoria Australia 3Department of Biochemistry and Molecular Biology Monash University Melbourne Victoria Australia 4Department of Microbiology University of Iowa Iowa City Iowa USA and 5Department of Microbiology Monash University Melbourne Victoria Australia Email Dinushka Dowling - Somayeh Nasr-Esfahani - Chun H Tan - Kate O Brien - Jane L Howard - jlh@ David A Jans - Damian FJ Purcell - dfjp@ C Martin Stoltzfus - marty-stoltzfus@ Secondo Sonza - sonza@ Corresponding author Published 4 February 2008 Received 19 July 2007 Retrovirology 2008 5 18 doi 1742-4690-5-18 Accepted 4 February 2008 This article is available from http content 5 1 18 2008 Dowling et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Macrophages are important targets and long-lived reservoirs of HIV-1 which are not cleared of infection by currently available treatments. In the primary monocyte-derived macrophage model of infection replication is initially productive followed
