Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway. | Retrovirology BioMed Central Research Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway Pablo N Fernandez Larrosa 1 Diego O Croci2 Diego A Riva3 Mariel Bibini1 Renata Luzzi1 Mónica Saracco1 Susana E Mersich3 Gabriel A Rabinovich2 and Liliana Martinez Peralta1 Open Access Address National Reference Center for AIDS Department of Microbiology School of Medicine University of Buenos Aires Buenos Aires Argentina laboratory of Immunopathology Institute of Biology and Experimental Medicine IBYME CONICET Buenos Aires Argentina and laboratory of Virology Department of Biochemistry School of Exact and Natural Sciences University of Buenos Aires Buenos Aires Argentina Email Pablo N Fernandez Larrosa - plarrosa@ Diego O Croci - dcrocirusso@ Diego A Riva - diegor@ Mariel Bibini - mbibini@ Renata Luzzi - rluzzi@ Mónica Saracco - msaracco@ Susana E Mersich - susanm@ Gabriel A Rabinovich - gabyrabi@ Liliana Martinez Peralta - lilimp@ Corresponding author Published 8 February 2008 Received II October 2007 Retrovirology 2008 5 19 doi 1742-4690-5-19 Accepted 8 February 2008 This article is available from http content 5 1 19 2008 Fernández Larrosa et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background HIV triggers the decline of CD4 T cells and leads to progressive dysfunction of cell-mediated immunity. Although an increased susceptibility to cell death occurs during the acute phase of HIV .

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