Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery: a pilot randomized controlled trial. | Available online http content 11 5 R100 Research Goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery a pilot randomized controlled trial Marcel R Lopes1 Marcos A Oliveira1 Vanessa Oliveira S Pereira1 Ivaneide Paula B Lemos1 Jose Otavio C Auler Jr2 and Frédéric Michard3 1 Department of Anesthesia and Critical Care Santa Casa de Misericórdia de Passos 164 rua Santa Casa 37900-020 Passos MG Brazil 2Department of Anesthesia and Critical Care INCOR-University of São Paulo 44 Dr. Enéas de Carvalho Aguiar Avenida 05403-000 São Paulo SP Brazil 3Department of Anesthesia and Critical Care Béclère Hospital - University Paris XI 157 rue de la Porte de Trivaux 92141 Clamart France Corresponding author Frédéric Michard Received 30 Apr 2007 Accepted 7 Sep 2007 Published 7 Sep 2007 Critical Care 2007 11 R100 doi cc6117 This article is online at http content 11 5 R1 00 2007 Lopes et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Several studies have shown that maximizing stroke volume or increasing it until a plateau is reached by volume loading during high-risk surgery may improve post-operative outcome. This goal could be achieved simply by minimizing the variation in arterial pulse pressure APP induced by mechanical ventilation. We tested this hypothesis in a prospective randomized single-centre study. The primary endpoint was the length of postoperative stay in hospital. Methods Thirty-three patients undergoing high-risk surgery were randomized either to a control group group C n 16 or to an intervention group group I n 1 7 . In group I APP was continuously monitored during surgery by a .
