Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework. | Available online http content 11 6 233 Review Clinical review Treatment of new-onset atrial fibrillation in medical intensive care patients - a clinical framework Mengalvio E Sleeswijk1 Trudeke Van Noord2 Jaap E Tulleken2 Jack JM Ligtenberg2 Armand RJ Girbes3 and Jan G Zijlstra2 1 Flevo Hospital Hospitaalweg 1 1315 RA Almere The Netherlands 2Department of Intensive Care University Medical Center Groningen University of Groningen PO 9700 RB Groningen The Netherlands 3Department of Intensive Care University Hospital VU Medical Centre Boelelaan 1117 1081 HV Amsterdam The Netherlands Corresponding author Jan G Zijlstra Published 12 November 2007 This article is online at http content 11 6 233 2007 BioMed Central Ltd Critical Care 2007 11 233 doi cc6136 Abstract Atrial fibrillation occurs frequently in medical intensive care unit patients. Most intensivists tend to treat this rhythm disorder because they believe it is detrimental. Whether atrial fibrillation contributes to morbidity and or mortality and whether atrial fibrillation is an epiphenomenon of severe disease however are not clear. As a consequence it is unknown whether treatment of the arrhythmia affects the outcome. Furthermore if treatment is deemed necessary it is not known what the best treatment is. We developed a treatment protocol by searching for the best evidence. Because studies in medical intensive care unit patients are scarce the evidence comes mainly from extrapolation of data derived from other patient groups. We propose a treatment strategy with magnesium infusion followed by amiodarone in case of failure. Although this strategy seems to be effective in both rhythm control and rate control the mortality remained high. A randomised controlled trial in medical intensive care unit patients with placebo treatment in the control arm is therefore still defendable. Introduction Atrial fibrillation AF is frequently observed in the medical
