Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Improvements in the outcome of children with meningococcal disease. | Available online http content 11 5 172 Commentary Improvements in the outcome of children with meningococcal disease Fauzia Paize1 and Stephen D Playfor2 Institute of Child Health University of Liverpool Eaton Road Liverpool L12 2AP United Kingdom 2Paediatric Intensive Care Unit Royal Manchester Children s Hospital Hospital Road Pendlebury Manchester M27 4HA United Kingdom Corresponding author Stephen D Playfor Published 29 October 2007 This article is online at http content 11 5 172 2007 BioMed Central Ltd Critical Care 2007 11 172 doi cc6140 See related research by Maat et al. http content 11 5 R112 Abstract Recent years have seen a marked reduction in the mortality of children with meningococcal disease in paediatric intensive care units PICU the reasons for this improvement are multifactorial. The mortality rates for critically ill children overall have improved and reasons for this are probably increased centralisation of PICU services and that fewer critically ill children are now looked after on adult units. Specific treatment pathways for sepsis have improved with the publication of clinical guidelines for children and initiatives such as the Surviving Sepsis Campaign. There is a continuing need to focus on the care delivered to children before reaching PICU and to minimise the morbidity suffered by survivors of this disease. Meningococcal disease MCD continues to be the most common infective cause of death in children. In this issue of the journal Maat et al. describe a paediatric intensive care unit PICU based study describing their experience of managing children with MCD specifically sepsis and purpura over an 18 year period 1 . They are in the unusual and valuable position of having collected their data prospectively. The authors found that survival of children presenting to their unit with MCD correlated with year of admission indicating a significant ongoing reduction in case .
