Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Formulas Hypothermia and cardiac arrest: the promise of intra-arrest cooling. | Available online http content 12 2 138 Commentary Hypothermia and cardiac arrest the promise of intra-arrest cooling Roger A Band1 2 and Benjamin S Abella1 2 1 Department of Emergency Medicine University of Pennsylvania 3400 Spruce Street Ground Ravdin Philadelphia PA 19104 USA 2Center for Resuscitation Science University of Pennsylvania 3400 Spruce Street Ground Ravdin Philadelphia PA 19104 USA Corresponding author Benjamin S Abella Published 22 April 2008 This article is online at http content 12 2 138 2008 BioMed Central Ltd Critical Care 2008 12 138 doi cc6845 See related research by Bruel et al. http content 12 1 R31 Abstract Over the past several years the implementation of therapeutic hypothermia has provided an exciting opportunity toward improving survival from out-of-hospital cardiac arrest. There are compelling data to support the prompt use of therapeutic hypothermia for initial survivors from out-of-hospital cardiac arrest but animal data have suggested that initiation of therapeutic hypothermia during the intra-arrest period may significantly improve outcomes even further. In the first feasibility study in humans Bruel and colleagues report on the implementation of this intra-arrest approach among patients suffering out-of-hospital cardiac arrest an exciting prospect that is discussed in the present commentary. In the last issue of Critical Care Bruel and colleagues report findings from a small prospective observational study in which they investigate the feasibility efficacy and safety of intra-arrest therapeutic hypothermia TH for victims of out-ofhospital cardiac arrest OHCA 1 . From an initial pool of 412 cardiac arrest victims the study enrolled 33 patients with a variety of presenting rhythms. This represents the first study of its kind to investigate the feasibility of intra-arrest cooling in the clinical setting an approach that has shown significant promise in animal .
