Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Circulating plasma factors induce tubular and glomerular alterations in septic burns patients. | Available online http content 1 2 2 R42 Research Circulating plasma factors induce tubular and glomerular alterations in septic burns patients Filippo Mariano1 Vincenzo Cantaluppi2 Maurizio Stella3 Giuseppe Mauriello Romanazzi2 Barbara Assenzio4 Monica Cairo3 Luigi Biancone2 Giorgio Triolo1 V Marco Ranieri4 and Giovanni Camussi2 Open Access 1Dipartimento di Area Medica Unita di Nefrologia e Dialisi Ospedale CTO Via G. Zuretti 29 Torino 10126 Italy 2Dipartimento di Medicina Interna Centro Interdipartimentale di Biotecnologie Molecolari e Centro Ricerca Medicina Sperimentale CeRMS Universita di Torino Corso Dogliotti 14 Torino 10126 Italy 3Dipartimento di Chirurgia Plastica Centro Grandi Ustionati Ospedale CTO Via G. Zuretti 29 Torino 10126 Italy 4Dipartimento di Anestesiologia e Rianimazione Università di Torino Ospedale S Giovanni Battista-Molinette Corso Dogliotti 14 Torino 10126 Italy Contributed equally Corresponding author Giovanni Camussi Received 7 Dec 2007 Revisions requested 9 Jan 2008 Revisions received 8 Feb 2008 Accepted 25 Mar 2008 Published 25 Mar 2008 Critical Care 2008 12 R42 doi cc6848 This article is online at http content 12 2 R42 2008 Mariano et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Severe burn is a systemic illness often complicated by sepsis. Kidney is one of the organs invariably affected and proteinuria is a constant clinical finding. We studied the relationships between proteinuria and patient outcome severity of renal dysfunction and systemic inflammatory state in burns patients who developed sepsis-associated acute renal failure ARF . We then tested the hypothesis that plasma in these patients induces .