Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: A reflection on HIV/AIDS research after 25 years. | Retrovirology BioMed Central Commentary A reflection on HIV AIDS research after 25 years Robert C Gallo Open Access Address Institute of Human Virology University of Maryland Biotechnology Institute and Department of Microbiology and Immunology University of Maryland School of Medicine Baltimore Maryland 21201 USA Email Robert C Gallo - gallo@ Corresponding author Published 20 October 2006 Received 04 October 2006 Accepted 20 October 2006 Retrovirology 2006 3 72 doi 1742-4690-3-72 This article is available from http content 3 1 72 2006 Gallo licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Dr. Robert C. Gallo provides a personal reflection on the 25 year history of AIDS. Reflection A reflection on the 25 year history of AIDS can begin with no better outline than that provided by the late Jonathan Mann of WHO. A slide he gave to me in the late 1980 s divides the history of AIDS into four periods see fig. 1 . Jonathan could not know that the period of silent spread part 1 of this saga of HIV actually began years earlier. We now know that by 1971 the virus had moved to several different regions of the world but exactly when it came out of Africa is conjectural. There has been considerable attention no less than three papers in Science and Nature over the past few years from B. Hahn and her colleagues that the natural reservoir for HIV-1 is a particular subspecies of chimp 1-3 . The pri-mate-to-man origin of HIV was suspected almost from the beginning albeit without knowing which primate. The reasons were three fold 1 the early evidence that HIV was widespread in central Africa 2 the evidence that HIV was more variable in Africa hence longer presence and 3 prior experience with
