Báo cáo y học: "Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: "Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. | Retrovirology BioMed Central Research Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection Koen KA Van Rompay 1 Jeffrey A Johnson2 Emily J Blackwood1 Raman P Singh1 Jonathan Lipscomb2 Timothy B Matthews3 Marta L Marthas1 Niels C Pedersen4 Norbert Bischofberger5 Walid Heneine2 and Thomas W North3 6 Open Access Address California National Primate Research Center University of California Davis USA 2Division of HIV AIDS Prevention National Center for HIV STD and Tuberculosis Prevention Centers for Disease Control and Prevention Atlanta USA Center for Comparative Medicine University of California Davis USA 4Department of Medicine and Epidemiology School of Veterinary Medicine University of California Davis USA 5Gilead Sciences Foster City USA and 6Department of Molecular Biosciences School of Veterinary Medicine University of California Davis USA Email Koen KA Van Rompay - kkvanrompay@ Jeffrey A Johnson - jlj6@ Emily J Blackwood - emib44@ Raman P Singh - Jonathan Lipscomb - eyk1@ Timothy B Matthews - tbmatthews@ Marta L Marthas - mlmarthas@ Niels C Pedersen - ncpedersen@ Norbert Bischofberger - Walid Heneine - wmh2@ Thomas W North - twnorth@ Corresponding author Published 6 April 2007 Received 16 January 2007 Retrovirology 2007 4 25 doi 1742-4690-4-25 Accepted 6 April 2007 This article is available from http content 4 1 25 2007 Van Rompay et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. .