Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cough reflex sensitivity improves with speech language pathology management of refractory chronic cough. | Ryan et al. Cough 2010 6 5 http content 6 1 5 RESEARCH w Cough Open Access Cough reflex sensitivity improves with speech language pathology management of refractory chronic cough Nicole M Ryan1 2 Anne E Vertigan1 3 Sarah Bone3 Peter G Gibson1 2 Abstract Rationale Speech language pathology is an effective management intervention for chronic cough that persists despite medical treatment. The mechanism behind the improvement has not been determined but may include active cough suppression reduced cough sensitivity or increased cough threshold from reduced laryngeal irritation. Objective measures such as cough reflex sensitivity and cough frequency could be used to determine whether the treatment response was due to reduced underlying cough sensitivity or to more deliberate control exerted by individual patients. The number of treatments required to effect a response was also assessed. Objective The aim of this study was to investigate subjective and objective measures of cough before during and after speech language pathology treatment for refractory chronic cough and the mechanism underlying the improvement. Methods Adults with chronic cough n 17 were assessed before during and after speech language pathology intervention for refractory chronic cough. The primary outcome measures were capsaicin cough reflex sensitivity automated cough frequency detection and cough-related quality of life. Results Following treatment there was a significant improvement in cough related quality of life Median IQR at baseline vs. post treatment p objective cough frequency Mean SD at baseline vs. post treatment 25 coughs hr p and cough reflex sensitivity Mean SD log C5 at baseline vs. post treatment p . Conclusions This is the first study to show that speech language pathology management is an effective intervention for refractory chronic cough and that the mechanism behind the improvement is due
