Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Recently published papers: predictors, pressors and poietins. | Available online http content 11 6 181 Commentary Recently published papers predictors pressors and poietins Suzannah Ward and Richard Venn Department of Critical Care Worthing General Hospital Worthing UK Corresponding author Suzie Ward suzieward@ Published 21 December 2007 This article is online at http content 11 6 181 2007 BioMed Central Ltd Critical Care 2007 11 181 doi cc6188 Abstract Simple sensitive and specific predictors of mortality in the critically ill remain elusive goals and brain natriuretic peptide and venous lactate are the subjects of recent studies. The role of vasopressin in sepsis continues to be the focus of much research interest. Dose ranging studies potential adverse effects and selective V1 agonists are discussed below in recent trials. Finally the use of erythropoietin in the critically ill continues to be studied but many continue to urge caution for widespread use outside of clinical trials. Predictors The search for simple sensitive and specific prognostic tools in the critically ill population continues in the current literature. Brain natriuretic peptide BNP has emerged during recent years as a helpful tool in patients with cardiac failure sepsis and acute myocardial infarction MI 1 . Meyer et al. investigated the prognostic impact of plasma N-terminal proB-type natriuretic peptide BNP in an unselected cohort of 289 critically ill patients on admission to the intensive care unit ICU 2 . ICU and hospital survivors had significantly lower BNP when compared to non survivors ICU BNP levels 3 394 versus 6 776 pg mL hospital BNP levels 2 656 versus 8 390 pg mL p . There were no significant differences in BNP values between those patients with a primary cardiac diagnosis compared to those with a non cardiac diagnosis. A logistic regression model showed that Simplified Acute Physiology Score SAPS and BNP were independently associated p . The authors concluded that BNP may facilitate
