Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care. | Available online http content 11 6 R128 Research A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis comparison of recombinant human activated protein C with standard care Christopher J Longo1 Daren K Heyland2 Harold N Fisher3 Robert A Fowler4 Claudio M Martin5 and Andrew G Day6 1McMaster University Main Street West Hamilton Ontario Canada L8S 4M4 2Kingston General Hospital Queen s University Stuart Street Kingston Ontario Canada K7L 2V7 3Eli Lilly Canada Inc. Danforth Avenue Scarborough Ontario Canada M1N 2E8 4Sunnybrook Health Sciences Centre Bayview Avenue Toronto Ontario Canada M4N 3M5 5London Health Sciences Centre Commissioners Road East London Ontario Canada N6A 5W9 6Clinical Research Centre Kingston General Hospital Stuart Street Kingston Ontario Canada K7L 2V7 Corresponding author Christopher J Longo cjlongo@ Received 18 Jul 2007 Revisions requested 6 Sep 2007 Revisions received 4 Oct 2007 Accepted 11 Dec 2007 Published 11 Dec 2007 Critical Care 2007 11 R128 doi cc6195 This article is online at http content 11 6 R1 28 2007 Longo et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Recombinant human activated protein C APC therapy has been shown to reduce short-term mortality in patients with severe sepsis. However survivors of sepsis may have long-term complications affecting health-related quality of life HRQoL and resource utilization. The objective of this study was to evaluate prospectively the effect of APC on long-term HRQoL and resource utilization compared with a nonrandomized control group that received standard care. Methods This was an observational cohort .
