Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Kerbs von Lungren 6 antigen is a marker of alveolar inflammation but not of infection in patients with acute respiratory distress syndrome. | Available online http content 1 2 1 R12 Research Kerbs von Lungren 6 antigen is a marker of alveolar inflammation but not of infection in patients with acute respiratory distress syndrome Nazim Nathani1 Gavin D Perkins2 William Tunnicliffe3 Nick Murphy3 Mav Manji3 and David R Thickett4 1Lung Injury and Fibrosis Treatment Program Department of Medical Sciences The Medical School University of Birmingham Edgbaston Birmingham B15 2TT UK department of Intensive Care Medicine Birmingham Heartlands Hospital Birmingham B9 5SS UK department of Critical Care University Hospital Birmingham Birmingham B152TH UK 4Lung Injury and Fibrosis Treatment Program Nuffield House Queen Elizabeth Hospital Department of Medicine University of Birmingham B15 2TH UK Corresponding author David RThickett Received 5 Oct 2007 Revisions requested 13 Nov 2007 Revisions received 4 Dec 2007 Accepted 23 Jan 2008 Published 23 Jan 2008 Critical Care 2008 12 R12 doi cc6785 This article is online at http content 12 1 R1 2 2008 Nathani et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Background Kerbs von Lungren 6 antigen KL-6 is expressed on the surface of alveolar type II cells and elevated plasma and epithelial lining fluid levels of KL-6 have previously been shown to correlate with the severity of disease and survival in acute respiratory distress syndrome ARDS . The relationship between alveolar inflammation and KL-6 measurements has not been ascertained. We hypothesized that the elevation of KL-6 in ARDS is dependent upon the severity of neutrophilic inflammation. Furthermore we were interested in the relationship between significant alveolar infection and KL-6 levels. Methods
