Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Corticosteroids for community-acquired pneumonia: time to act! | Available online http content 12 4 166 Commentary Corticosteroids for community-acquired pneumonia time to act Djillali Annane1 and G Umberto Meduri2 Service de réanimation hôpital Raymond Poincaré AP-HP Université de Versailles SQY UniverSud Paris 104 boulevard Raymond Poincaré 92380 Garches France 2University of Tennessee Health Science Center and Memphis Veterans Affairs Medical Center Division of Pulmonary Critical Care and Sleep Medicine 956 Court Avenue Room H316 Memphis TN 38163 USA Corresponding author Djillali Annane Published 14 July 2008 This article is online at http content 12 4 166 2008 BioMed Central Ltd Critical Care 2008 12 166 doi cc6940 See related research by Salluh et al. http content 12 3 R76 Abstract The use of corticosteroids for the treatment of community-acquired pneumonia has been reported for almost 50 years. A recent systematic analysis of the relevant literature suggested that corticosteroids reduce the critical illness associated with community-acquired pneumonia. There is little doubt that a prolonged administration of a moderate dose of corticosteroids may alleviate the systemic inflammatory response and subsequent organ dysfunction in severe infection. Whether these favorable effects on morbidity may translate into better survival and quality of life needs to be addressed in additional adequately powered randomized controlled trials. In the previous issue of Critical Care Salluh and colleagues 1 suggested evidence-based recommendations for corticosteroid therapy in community-acquired pneumonia. Corticosteroids have been used as an adjunct therapy for severe infection for roughly half a century. Contrasting with the clinical practice researchers are continuing to argue the pros and cons of this therapeutic approach 2 . What is the basis for corticosteroids in community-acquired pneumonia In the era of powerful antibiotics the likelihood of uncontrolled infection
