Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Memory-enhancing treatments reverse the impairment of inhibitory avoidance retention in sepsis-surviving rats. | Available online http content 1 2 5 R133 Research Memory-enhancing treatments reverse the impairment of inhibitory avoidance retention in sepsis-surviving rats Lisiane Tuon1 Clarissa M Comim1 Fabricia Petronilho2 Tatiana Barichello2 Ivan Izquierdo3 João Quevedo1 and Felipe Dal-Pizzol2 1Laboratório de Neurociências Programa de Pós-Graduaọão Ciências da Saúde Unidade Acadêmica de Ciências da Saúde Universidade do Extremo Sul Catarinense Av. Universitária 1105 88806-000 Criciúma SC Brasil 2Laboratório de Fisiopatologia Experimental Programa de Pós-Graduaọão em Ciências da Saúde Unidade Acadêmica de Ciências da Saúde Universidade do Extremo Sul Catarinense Av. Universitária 1105 88806-000 Criciúma SC Brasil 3Centro de Memória Instituto de Pesquisas Biomédicas Pontificia Universidade Católica do Rio Grande do Sul Av Ipiranga 6690 90610-000 Porto Alegre RS Brasil Corresponding author Felipe Dal-Pizzol piz@ Received 9 Sep 2008 Revisions requested 30 Sep 2008 Revisions received 6 Oct 2008 Accepted 28 Oct 2008 Published 28 Oct 2008 Critical Care 2008 12 R133 doi cc7103 This article is online at http content 12 5 R133 2008 Tuon et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Survivors from sepsis have presented with longterm cognitive impairment including alterations in memory attention concentration and global loss of cognitive function. Thus we evaluated the effects of memory enhancers in sepsissurviving rats. Methods The rats underwent cecal ligation and perforation CLP sepsis group with basic support saline at 50 mL kg immediately and 12 hours after CLP plus ceftriaxone at 30 mg kg and clindamycin at 25 mg kg 6 12 and 18 hours after CLP or .
