Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Extending international sepsis epidemiology: the impact of organ dysfunction. | Available online http content 13 1 120 Commentary Extending international sepsis epidemiology the impact of organ dysfunction Annette M Esper and Greg S Martin Division of Pulmonary Allergy and Critical Care Emory University School of Medicine 49 Jesse Hill Jr Drive FOB Atlanta GA 30303 USA Corresponding author Annette M Esper aesper@ Published 23 February 2009 This article is online at http content 13 1 120 2009 BioMed Central Ltd Critical Care 2009 13 120 doi cc7704 See related research by Blanco et al. http content 12 6 R158 Abstract In the previous issue of Critical Care Blanco and colleagues contributed to a growing body of literature on the international epidemiology of severe sepsis. Taken together these studies confirm that the sepsis incidence is high that the development of organ dysfunction is a major determinant of mortality and that the occurrence of organ dysfunction is influenced by chronic comorbid medical conditions. It is clear that early detection of organ dysfunction and serial sequential organ dysfunction scoring provides us with the best chance to optimize clinical care. Identifying factors that contribute to the development of organ dysfunction in sepsis will lead to the development of new treatment modalities that will reduce mortality. Future studies must therefore focus on the impact of new treatment modalities for preventing progression to multiple organ dysfunction syndrome and consequent mortality in sepsis. The sepsis syndrome is a disease entity of universal impact. Many studies have reported on the epidemiology of sepsis and from these findings we are constantly informed that sepsis is a disease that deserves attention. In past years there have been advances in our understanding of sepsis ranging from studies of epidemiology to pathophysiology to risk prediction and outcome. Overall we are in agreement that the sepsis syndrome is common expensive and associated with a remarkably .
