Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Multi-faceted, multi-versatile microarray: simultaneous detection of many viruses and their expression profiles | Retrovirology BioMed Central Commentary Open Access Multi-faceted multi-versatile microarray simultaneous detection of many viruses and their expression profiles Biehuoy Shieh1 and Ching Li 2 Address Department of Biochemistry Chung Shan Medical University 110 Sec. 1 Chien Kuo N. Rd. Taichung 402 Taiwan and 2Department of Microbiology and Immunology Chung Shan Medical University 110 Sec. 1 Chien Kuo N. Rd. Taichung 402 Taiwan Email Biehuoy Shieh - bhshieh@ Ching Li - chingli@ Corresponding author Published 26 May 2004 Received 13 March 2004 Accepted 26 May 2004 Retrovirology 2004 1 11 This article is available from http content l l l I 2004 Shieh and Li licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract There are hundreds of viruses that infect different human organs and cause diseases. Some fatal emerging viral infections have become serious public health issues worldwide. Early diagnosis and subsequent treatment are therefore essential for fighting viral infections. Current diagnostic techniques frequently employ polymerase chain reaction PCR -based methods to quickly detect the pathogenic viruses and establish the etiology of the disease or illness. However the fast PCR method suffers from many drawbacks such as a high false-positive rate and the ability to detect only one or a few gene targets at a time. Microarray technology solves the problems of the PCR limitations and can be effectively applied to all fields of molecular medicine. Recently a report in Retrovirology described a multi-virus DNA array that contains more than 250 open reading frames from eight human viruses including human immunodeficiency virus type l. This array can be used to detect multiple viral co-infections in cells and in vivo. Another benefit of this kind of .
