Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Dermatology for the practicing allergist: Tinea pedis and its complications. | Clinical and Molecular Allergy BioMed Central Review Open Access Dermatology for the practicing allergist Tinea pedis and its complications Muhannad Al Hasan1 S Matthew Fitzgerald1 Mahnaz Saoudian1 and Guha Krishnaswamy 1 2 Address department of Internal Medicine James H. Quillen College of Medicine East Tennessee State University Johnson City TN 37614 USA and 2James H. Quillen . Medical Center Mountain Home Tennessee USA Email Muhannad Al Hasan - alhasan@ S Matthew Fitzgerald - fitzgers@ Mahnaz Saoudian - Saoudian@ Guha Krishnaswamy - krishnas@ Corresponding author Published 29 March 2004 Received 25 November 2003 Accepted 29 March 2004 Clinical and Molecular Allergy 2004 2 5 H This article is available from http content 2 1 5 2004 Al Hasan et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Tinea pedis is a chronic fungal infection of the feet very often observed in patients who are immuno-suppressed or have diabetes mellitus. The practicing allergist may be called upon to treat this disease for various reasons. Sometimes tinea infection may be mistaken for atopic dermatitis or allergic eczema. In other patients tinea pedis may complicate allergy and asthma and may contribute to refractory atopic disease. Patients with recurrent cellulitis may be referred to the allergist immunologist for an immune evaluation and discovered to have tinea pedis as a predisposing factor. From a molecular standpoint superficial fungal infections may induce a type2 T helper cell response Th2 that can aggravate atopy. Th2 cytokines may induce eosinophil recruitment and immunoglobulin E IgE class switching by B cells thereby leading to exacerbation of atopic conditions. Three groups of fungal pathogens referred to as dermatophytes