Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Non-allergic rhinitis: a case report and review. | Nozad et al. Clinical and Molecular Allergy 2010 8 1 http content 8 1 1 REVIEW CMA CLINICAL AND MOLECULAR ALLERGY Open Access Non-allergic rhinitis a case report and review Cyrus H Nozad 1 L Madison Michael2 3 D Betty Lew1 Christie F Michael1 Abstract Rhinitis is characterized by rhinorrhea sneezing nasal congestion nasal itch and or postnasal drip. Often the first step in arriving at a diagnosis is to exclude or diagnose sensitivity to inhalant allergens. Non-allergic rhinitis NAR comprises multiple distinct conditions that may even co-exist with allergic rhinitis AR . They may differ in their presentation and treatment. As well the pathogenesis of NAR is not clearly elucidated and likely varied. There are many conditions that can have similar presentations to NAR or AR including nasal polyps anatomical mechanical factors autoimmune diseases metabolic conditions genetic conditions and immunodeficiency. Here we present a case of a rare condition initially diagnosed and treated as typical allergic rhinitis vs. vasomotor rhinitis but found to be something much more serious. This case illustrates the importance of maintaining an appropriate differential diagnosis for a complaint routinely seen as mundane. The case presentation is followed by a review of the potential causes and pathogenesis of NAR. Introduction The term rhinitis can be used to describe many distinct entities with varying pathogeneses despite similar presentations. Generally rhinitis is considered allergic if significant inhalant allergy is diagnosed and is considered non-allergic when symptomatology is perennial or periodic and not IgE mediated. Thus non-allergic rhinitis NAR comprises a mixed bag of conditions ranging from vasomotor rhinitis VMR to hormonally induced rhinitis. Overall rhinitis results in significant cost to the world population. In 2002 the direct and indirect costs for allergic rhinitis AR were estimated to be billion and billion .
