Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Significant differences in alkaloid content of Coptis chinensis (Huanglian), from its related American species. | Chinese Medicine BioMed Central Open Access Significant differences in alkaloid content of Coptis chinensis Huanglian from its related American species Shreya Kamath1 Matthew Skeels1 and Aswini Pai 2 Address Department of Chemistry St Lawrence University Canton New York 13617 USA and 2Department of Biology St Lawrence University Canton New York 13617 USA Email Shreya Kamath - sakama04@ Matthew Skeels - mskeels@ Aswini Pai - apai@ Corresponding author Published 24 August 2009 Received 13 January 2009 Accepted 24 August 2009 Chinese Medicine 2009 4 17 doi 86 1749-8546-4-17 This article is available from http content 4 1 17 2009 Kamath et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The growing popularity of Chinese herbal medicine in the United States has prompted large-scale import of raw herbs from Asia. Many of the Asian herbs have phylogenetically related North American species. We compared three phylogenetically related species namely Coptis chinensis Huanglian Hydrastis canadensis and Coptis trifolia to show whether they can be substituted by one another in terms of alkaloid content. Methods We used microwave assisted extraction to obtain alkaloids berberine coptisine palmatine and hydrastine. High performance liquid chromatography HPLC was used to quantify each alkaloid. Results Hydrastis canadensis has the most berberine whereas Coptis trifolia has the most coptisine. Hydrastine and palmatine were unique to Hydrastis canadensis and Coptis chinensis respectively. Conclusion Neither Hydrastis canadensis nor Coptis trifolia contains all the alkaloids found in Coptis chinensis used in Chinese medicine. Substitutes of this Chinese species by .
