Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Differential influence of arterial blood glucose on cerebral metabolism following severe traumatic brain injury. | Available online http content 13 1 R13 Research Differential influence of arterial blood glucose on cerebral metabolism following severe traumatic brain injury Monika Holbein1 Markus Béchir1 Silke Ludwig1 Jutta Sommerfeld1 Silvia R Cottini1 Marius Keel2 Reto Stocker1 and John F Stover1 Open Access 1Surgical Intensive Care Medicine University Hospital Zuerich Raemistrasse 100 Zuerich 8091 Switzerland 2Department of Surgery Division of Trauma Surgery University Hospital Zuerich Raemistrasse 1 00 Zuerich 8091 Switzerland Corresponding author John F Stover Received 5 Sep 2008 Revisions requested 15 Oct 2008 Revisions received 1 Dec 2008 Accepted 6 Feb 2009 Published 6 Feb 2009 Critical Care 2009 13 R13 doi cc7711 This article is online at http content 13 1 R13 2009 Holbein et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Maintaining arterial blood glucose within tight limits is beneficial in critically ill patients. Upper and lower limits of detrimental blood glucose levels must be determined. Methods In 69 patients with severe traumatic brain injury TBI cerebral metabolism was monitored by assessing changes in arterial and jugular venous blood at normocarbia partial arterial pressure of carbon dioxide paCO2 to kPa normoxia partial arterial pressure of oxygen paO2 9 to 20 kPa stable haematocrit 27 to 36 brain temperature 35 to 38 C and cerebral perfusion pressure CPP 70 to 90 mmHg. This resulted in a total of 43 896 values for glucose uptake lactate release oxygen extraction ratio OER carbon dioxide CO2 and bicarbonate HCO3 production jugular venous oxygen saturation SjvO2 oxygen-glucose index OGI lactate-glucose index LGI and .
