Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Prediction of extubation outcome: a randomised, controlled trial with automatic tube compensation vs. pressure support ventilation. | Available online http content 13 1 R21 Research Prediction of extubation outcome a randomised controlled trial with automatic tube compensation vs. pressure support ventilation Jonathan Cohen Maury Shapiro Elad Grozovski Ben Fox Shaul Lev and Pierre Singer General Intensive Care Unit Rabin Medical Center Beilinson Campus Petah Tikva 49100 Israel Corresponding author Jonathan Cohen jonatanc@ Received 10 Sep 2008 Revisions requested 25 Oct 2008 Revisions received 6 Jan 2009 Accepted 23 Feb 2009 Published 23 Feb 2009 Critical Care 2009 13 R21 doi cc7724 This article is online at http content 13 1 R21 2009 Cohen et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Tolerance of a spontaneous breathing trial is an evidence-based strategy to predict successful weaning from mechanical ventilation. Some patients may not tolerate the trial because of the respiratory load imposed by the endotracheal tube so varying levels of respiratory support are widely used during the trial. Automatic tube compensation ATC specifically developed to overcome the imposed work of breathing because of artificial airways appears ideally suited for the weaning process. We further evaluated the use of ATC in this setting. Methods In a prospective study patients who had received mechanical ventilation for more than 24 hours and met defined criteria for a weaning trial underwent a one-hour spontaneous breathing trial with either ATC n 87 or pressure support ventilation PSV n 93 . Those tolerating the trial were immediately extubated. The primary outcome measure was the ability to maintain spontaneous unassisted breathing for more than 48 hours after extubation. In addition we .
