Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Resuscitation of hemorrhagic shock with normal saline versus lactated Ringer’s: effects on oxygenation, extravascular lung water, and hemodynamics. | Available online http content 13 2 128 Commentary Resuscitation of hemorrhagic shock with normal saline versus lactated Ringer s effects on oxygenation extravascular lung water and hemodynamics Samir G Sakka Department of Anesthesiology and Intensive Care Medicine Medical Center Cologne-Merheim University of Witten Herdecke Ostmerheimerstrasse 200 51109 Cologne Germany Corresponding author Samir G Sakka SakkaS@ Published 3 April 2009 This article is online at http content 13 2 128 2009 BioMed Central Ltd Critical Care 2009 13 128 doi cc7742 See related research by Phillips et al. http content 13 2 R30 Abstract Which type of fluid to use in the resuscitation from hemorrhagic shock within and between crystalloids or colloids is still a matter of debate. In this context with respect to organ dysfunction early detection of lung injury is widely considered of particular clinical importance. For these purposes the transpulmonary thermodilution technique that enables one to assess extravascular lung water as a marker of pulmonary edema is applied in the clinical setting. In this issue of Critical Care Phillips and colleagues describe that early resuscitation of hemorrhagic shock in pigs with two different crystalloid solutions - normal saline or Ringer s lactate - had little impact on oxygenation when the resuscitation volume was 250 ml kg. Ringer s lactate had more favorable effects than normal saline however on extravascular lung water pH and blood pressure but not on oxygenation. Although several pathophysiological aspects remain unanswered these data are interesting in so far as they indicate that clinically applied amounts of crystalloids per se do not negatively influence pulmonary function while with larger amounts the type of fluid has different effects on the extent of fluid extravasation in the lungs. In the present issue of Critical Care an experimental model of hemorrhagic shock in pigs describes a .
