Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Crystalloids versus colloids for goal-directed fluid therapy in major surgery. | Available online http content 13 2 R40 Research Crystalloids versus colloids for goal-directed fluid therapy in major surgery Luzius B Hiltebrand1 Oliver Kimberger2 Michael Arnberger1 Sebastian Brandt1 Andrea Kurz3 and Gisli H Sigurdsson4 1 Department of Anaesthesiology and Pain Therapy Inselspital Bern University Hospital Freiburgstrasse Bern CH 3010 Switzerland 2Department of Anaesthesia General Intensive Care and Pain Medicine Medical University of Vienna Wahringer Gurtel 18-20 Vienna A 1090 Austria 3Department of Outcomes Research The Cleveland Clinic 9500 Euclid Avenue Cleveland OH 44195 USA 4Department of Anaesthesia and Intensive Care Medicine Landspitali University Hospital and University of Iceland Hringbraut Reykjavik IS 101 Iceland Corresponding author Luzius B Hiltebrand Received 4 Nov 2008 Revisions requested 24 Dec 2008 Revisions received 20 Feb 2009 Accepted 21 Mar 2009 Published 21 Mar 2009 Critical Care 2009 13 R40 doi cc7761 This article is online at http content 13 2 R40 2009 Hiltebrand et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Perioperative hypovolemia arises frequently and contributes to intestinal hypoperfusion and subsequent postoperative complications. Goal-directed fluid therapy might reduce these complications. The aim of this study was to compare the effects of goal-directed administration of crystalloids and colloids on the distribution of systemic hepatosplanchnic and microcirculatory small intestine blood flow after major abdominal surgery in a clinically relevant pig model. Methods Twenty-seven pigs were anesthetized and mechanically ventilated and underwent open laparotomy. They were .