Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Heliox reduces respiratory system resistance in respiratory syncytial virus induced respiratory failure. | Available online http content 13 3 R71 Research Heliox reduces respiratory system resistance in respiratory syncytial virus induced respiratory failure Martin CJ Kneyber1 2 Marc van Heerde1 Jos WR Twisk3 Frans B Plotz1 and Dick G Markhors1 Department of Pediatric Intensive Care VU university medical center Amsterdam The Netherlands department of Pediatric Intensive Care Beatrix Children s Hospital University Medical Center Groningen Groningen The Netherlands 3Department of Biostatistics VU university medical center Amsterdam The Netherlands Corresponding author Martin CJ Kneyber Received 12 Dec 2008 Revisions requested 3 Feb 2009 Revisions received 20 Apr 2009 Accepted 15 May 2009 Published 15 May 2009 Critical Care 2009 13 R71 doi cc7880 This article is online at http content 13 3 R71 2009 Kneyber et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Respiratory syncytial virus RSV lower respiratory tract disease is characterised by narrowing of the airways resulting in increased airway resistance air-trapping and respiratory acidosis. These problems might be overcome using helium-oxygen gas mixture. However the effect of mechanical ventilation with heliox in these patients is unclear. The objective of this prospective cross-over study was to determine the effects of mechanical ventilation with heliox 60 40 versus conventional gas on respiratory system resistance air-trapping and CO2 removal. Methods Mechanically ventilated sedated and paralyzed infants with proven RSV were enrolled within 24 hours after paediatric intensive care unit PICU admission. At T 0 respiratory system mechanics including respiratory system compliance and .
