Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: When once is not enough – further evidence of procalcitonin-guided antibiotic stewardship. | Available online http content 13 4 165 Commentary When once is not enough - further evidence of procalcitonin-guided antibiotic stewardship Stephan Harbarth1 Werner C Albrich2 and Beat Muller2 11nfection Control Program Department of Internal Medicine University of Geneva Hospitals and Medical School CH-1211 Geneva 14 Switzerland 2Department of Internal Medicine Kantonsspital Aarau CH-5001 Aarau Switzerland Corresponding author Stephan Harbarth Published 13 July 2009 This article is online at http content 13 4 165 2009 BioMed Central Ltd Critical Care 2009 13 165 doi cc7935 See related research by Hochreiter et al. http content 13 3 R83 Abstract Every day critical care physicians around the world face the same challenge of the optimal timing of antimicrobial administration when to start and when to stop antibiotics. Duration of antibiotic therapy for sepsis is mostly based on expert opinion but its reduction is arguably the most promising approach to decrease emergence and selection of antibiotic resistance. The study by Hochreiter and colleagues presents another piece of evidence suggesting that procalcitonin may indeed be a valuable diagnostic parameter to guide antibiotic treatment duration despite the ongoing controversy about the diagnostic accuracy of procalcitonin. In the previous issue of Critical Care Hochreiter and colleagues presented another piece of evidence suggesting that proealeitonin PCT may indeed be a valuable diagnostic parameter to guide antibiotic treatment duration 1 . Misuse of antimicrobial agents has been a long-lasting problem in intensive care units ICUs . Drivers of inappropriate prescribing include diagnostic uncertainty lack of knowledge unavailability of microbiologic support or infectious disease specialists pharmaceutical marketing pressure and the overarching fear of missing a life-threatening infection. Every day critical care physicians around the world face .
